@Joe: that is very true. Awareness of how these pole play out on the 'canvas' is of paramount importance to good modeling.
I seem to be reiterating myself from time to time. I want to keep stressing that for organic modeling it is important to blend the loops. And talking about pairs, there is nothing better than to separate those pairs, and preferably as far from each other as possible.
Before you say: "again another diagram?

". Be patient, I'm going somewhere with this. I can go model a muscular monster intuitively, but I wanted to lay it out as clear as possible before we can go crazy.
I began with a circular loop. I moved the circled N-pole E-pole twins form each other. Observe that all poles are still in the same circular loop. Normally E-poles and N-poles are joined together by that extra diagonal edge of the E-pole (green), but break that bond, and your topology blends better. There is also an extra loop here (yellow: the N-pole bends it both ways here). You can see that the separated E-pole causes nice diagonal flows.
I don't think that modeling a face should be difficult by now. The human face/ head has a relative simple topology (ears not included). Fantasy creatures (see Golem's head topology for example), muscular bodies and such are a lot harder.
If no sudden discoveries comes in between, I'll be talking about limbs, how the loops should flow around the root of the limb to connect to the muscular feature of the main body.